Explores the intrinsic pathway of coagulation and is a screening test to investigate some congenital or acquired deficiencies, especially hemophilia A and B, or coagulation inhibitors such as Lupus Anticoagulant (LA) or autoantibodies against coagulation factors.

* cf Dedicated instructions for use

• CEPHEN™
  Liquid aPTT Ready to use

  Determination of aPTT.

  Reference	Registration	Presentation
  CK511K	CE-IVD	6 x 1 mL
  CK512K	CE-IVD	6 x 2.5 mL
  CK515K	CE-IVD	8 x 5 mL
  CK515L	CE-IVD	12 x 5 mL

  IFU APPLICATION SDS COT TABLE OF ASSIGNED VALUE

  
• CEPHEN™ LS
  Liquid aPTT Lupus sensitive Ready to use

  Determination of aPTT.
  This reagent offers a good sensitivity to the presence of LA.

  Reference	Registration	Presentation
  CK521K	CE-IVD	6 x 1 mL
  CK522K	CE-IVD	6 x 2.5 mL

  IFU APPLICATION SDS COT TABLE OF ASSIGNED VALUE

  

Elevated fibrinogen concentrations are observed in inflammation and have also been considered as a risk factor for cardiovascular disease and thrombosis.
Hypofibrinogenemia can be present in patients with fibrinogen deficiency or dysfunction (abnormal protein), and is also associated with severe liver diseases, or excessive consumption (Disseminated Intravascular Coagulation (DIC)).
Numerous variants of fibrinogen have been described, and are associated to asymptomatic cases or hypofibrinogenemia, with clinical manifestations of bleeding, or thrombosis (resulting from an impaired fibrinolysis).

* cf Dedicated instructions for use

• FIBRIPHEN™ LRT
  Liquid and Ready to use

  Measurement of the fibrinogen concentration in plasma using the von Clauss method. This reagent is available with the lyophilized presentation, or the ready to use liquid format.

  Reference	Registration	Presentation
  CK585K	CE-IVD	6 x 5 mL

  IFU APPLICATION SDS COT TABLE OF ASSIGNED VALUE

  
• FIBRIPHEN™

  Measurement of the fibrinogen concentration in plasma using the von Clauss method. This reagent is available with the lyophilized presentation, or the ready to use liquid format.

  Reference	Registration	Presentation
  CK571K	CE-IVD	6 x 1 mL
  CK572K	CE-IVD	6 x 2 mL
  CK575K	CE-IVD	8 x 5 mL

  IFU APPLICATION SDS COT TABLE OF ASSIGNED VALUE

  
• LIAPHEN™ Fibrinogen
  Liquid and Ready to use

  Determination of Fibrinogen antigen (Fib:Ag) in human citrated plasma or in purified medium, using a latex turbidimetric assay.

  Reference	Registration	Presentation
  120102	CE-IVD	4 x 5 mL

  IFU APPLICATION SDS COT TABLE OF ASSIGNED VALUE

  
• ZYMUTEST™ Fibrinogen
  

  Measurement of human Fibrinogen in plasma, or in any fluid where Fibrinogen can be present, with an Elisa method.

  Reference	Registration	Presentation
  RK024A	RUO	96 tests

  IFU APPLICATION SDS COT TABLE OF ASSIGNED VALUE

  

TT is a screening test to assess abnormalities of fibrinogen and to detect thrombin inhibitors. It can be useful for the exploration of Disseminated Intravascular Coagulation (DIC) and liver diseases.
A prolonged TT can result from the presence of antithrombin activity induced by therapy (e.g. Heparin, Bivalirudin, Argatroban, Dabigatran), the presence of high concentrations of Fibrin/Fibrinogen degradation products or qualitative (dysfibrinogenemia) or quantitative abnormalities of Fibrinogen (deficiency, DIC, fibrinolysis, hepatic disorders including cirrhosis).
TT is normal in presence of a Factor XIII deficiency.

* cf Dedicated instructions for use

• HEMOCLOT™ Thrombin Time LRT
  Liquid and Ready to use

  Determination of TT in human citrated plasma.

  Reference	Registration	Presentation
  CK012K	CE-IVD	6 x 5 mL

  IFU APPLICATION SDS COT TABLE OF ASSIGNED VALUE

  
• HEMOCLOT™ Thrombin Time (T.T.)

  Determination of TT in human citrated plasma.

  Reference	Registration	Presentation
  CK011K	CE-IVD	6 x 2 mL
  CK011L	CE-IVD	6 x 8 mL

  IFU APPLICATION SDS COT TABLE OF ASSIGNED VALUE